OPPORTUNITIES AND CHALLENGES OF DELIVERING DIGITAL CLINICAL TRIALS: LESSONS LEARNED FROM A RANDOMISED CONTROLLED TRIAL OF AN ONLINE BEHAVIOURAL INTERVENTION FOR CHILDREN AND YOUNG PEOPLE

Abstract Background Despite being the gold standard of research to determine effectiveness, randomised controlled trials (RCTs) often struggle with participant recruitment, engagement and retention.These issues may be exacerbated when recruiting vulnerable populations, such as participants with mental health issues.We aimed to update understanding

Choledochal cysts are rare congenital anomalies that have a variable presentation with occasional diagnostic and therapeutic dilemmas.Our case Strips is a 14-year female presented with recurrent abdomen pain with confusing diagnostic findings, suggestive of a large choledochal cyst (22x29x17cm) initially managed by percutaneous tube biliary drainag

This paper aims at understanding how the subject-object dualism is present in judgments of the Courts.How to ensure the effectiveness of the Code of Civil Procedure before the conscience of the magistrate and the paradigms highlighted here? Demonstrates that the philosophy of language influences how decisions are made in Court.So the objective is t

Skimmers and Strainers Rectal cancer management has evolved significantly, particularly with neoadjuvant treatment strategies.This narrative review examines the development and effectiveness of these therapies for locally advanced rectal cancer (LARC), highlighting the historical quest that led to current neoadjuvant alternatives.Initially, trials

Intranasal delivery provides a practical, noninvasive method of bypassing the blood-brain barrier (BBB) in order to deliver therapeutic agents to the brain.This method allows drugs that do not cross the BBB to be delivered Vanity Stool to the central nervous system in a few minutes.With this technology, it will be possible to eliminate systemic adm